Selection bias in clinical sciences: Difference between revisions

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retrospective study is the topic of this task.
 
The genuine, historical example (only partially approximated in this task) is of a study done of persons who, over a course
of 180 days, may or may not have become infected with Covid-19. Prior to becoming ill, these subjects may or may not have taken an available medication, which was actually taken on a particular schedule not used here, but is approximated by stating the medication was taken in doses of 3, 6, or 9 mg daily. The historical study then divided its subjects into three groups based on their cumulative dosage of the study medication:
or may not have taken an available medication, which was usually taken in doses of 3, 6, or 9 mg daily.
The historical study divided its subjects into three groups based on their cumulative dosage of the
study medication:
 
* Group UNTREATED were those who did not take the study medication at all before they got Covid-19, including those who exited the study period without Covid-19 and having never taken the study medication.
 
* Group IRREGULAR is those who took the study medication but whose cumulative dose was less than a certain amount (approximated for our purposes as 100 mg) before they either came down with Covid-19 during the study or the study period ended.
 
* Group REGULAR is those who took (our approximation is >= 100 mg) of the study medication either before thaythey came down with Covid-19 or took >= 100 mg by the end of the study and never became infected during the study.
 
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* The probability of starting treatment medication for anyone not already taking it was 0.5% per day. For those who started medication, the chance of continuing the treatment was increased 50-fold to 25% each day, since most who started the medication continued to take it to some extent.
* Study dose per day is random between the approximation for the simulation of 3, 6 and 9 mg. The daily cumulative dosage is used to determine the group the subject is in, unless a subject develops Covid-19. If a subject was diagnosed with Covid-19, their group at the time of that diagnosis is used in the statistical analysis of that group.
 
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* You should get a statistical result highly favoring the REGULAR group.
 
 
;Stretch task
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